Evidence-appraisal glossary

Post-test probability

The updated probability that a person has the condition after their test result is taken into account, obtained by combining the pre-test probability with the test's likelihood ratio.

Also called: posterior probability, posttest probability.

Post-test probability is what a clinician actually wants after ordering a test, and it is calculated by converting the pre-test probability to odds, multiplying by the likelihood ratio, and converting back. The positive predictive value is simply the post-test probability after a positive result, computed at one particular pre-test probability, namely the prevalence in the studied group. Because of that dependence, quoting a single post-test probability without stating the assumed pre-test probability can mislead.

This is a plain-language methodology definition for reading research. It is general education, not medical advice.

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